Histone H4 anticorps (meLys20)

N° du produit ABIN6254918

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H4 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Histone H4 anticorps (meLys20) (ABIN6254918)

Antigène: Histone H4

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Histone H4 anticorps

Épitope: meLys20

Specificité: Histone H4K20me1 Antibody detects endogenous levels of total Histone H4K20me1

Réactivité croisée: Humain, Souris

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthetic peptide corresponding to the amino terminus of histone H4 in which Lys20 is mono-methylated.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Histone H4

Antigène: Histone H4

Autre désignation: Histone H4K20me1

Sujet:

Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4

Poids moléculaire: 11kDa

ID gène: 121, 504, 554

UniProt: P62805